Kód: 06817958
Understanding forces in the context of biology is §essential as all cells in the human §body are constantly subjected to mechanical forces §and are often presented with situations where §adaptations are critical for survival. Mech ... celý popis
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Understanding forces in the context of biology is §essential as all cells in the human §body are constantly subjected to mechanical forces §and are often presented with situations where §adaptations are critical for survival. Mechanical §adaptations in response to forces have been studied §mainly though visualization of changes in §cytoskeletal structures and understanding the §corresponding signaling pathways. These §observations are informative in elucidating §regulating proteins and cellular phenotype, but do §not offer insights to the effects, or cell §mechanics, of these cellular changes and §regulations. A few important questions remain: 1) §what are the corresponding mechanical changes, 2) §how do these mechanical changes help the cell adapt, §3) is it possible these adaptations result in §unforeseen consequences, and 4) if so, do they §result in disease? Due to technical limitations, §only a portion of the answers have been explored to §date. In an attempt to answer these questions, we §present studies that use novel insights to quantify §changes in cell and nuclear mechanics and reveal the §potential impact forces play in cancer and aging.
Zařazení knihy Knihy v angličtině Technology, engineering, agriculture Industrial chemistry & manufacturing technologies Industrial chemistry
2076 Kč
Osobní odběr Praha, Brno a 12903 dalších
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