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Více informací o knize Protein-protein Complexes: Analysis, Modeling And Drug Design

• Parametry knihy
• Anotace
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Anotace knihy

Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge be used to predict and design protein-protein interactions (interaction regions and complex structures)? What methods are currently employed to design protein-protein interactions, and how can we influence protein-protein interactions by mutagenesis and small-molecule drugs or peptide mimetics? The book consists of about 15 review chapters, written by experts, on the characterization of protein-protein interfaces, structure determination of protein complexes (by NMR and X-ray), theory of protein-protein binding, dynamics of protein interfaces, bioinformatics methods to predict interaction regions, and prediction of protein-protein complex structures (docking and homology modeling of complexes, etcetera.) and design of protein-protein interactions. It serves as a bridge between studying/analyzing protein-protein complex structures (interfaces), predicting interactions, and influencing/designing interactions.

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Biology, life sciences Biochemistry

• Plný název: Protein-protein Complexes: Analysis, Modeling And Drug Design
• Autor: Martin Zacharias
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 400
• EAN: 9781848163393
• ISBN: 1848163398
• ID: 01357931
• Nakladatelství: Imperial College Press
• Hmotnost: 606 g
• Rozměry: 229 × 156 × 18 mm
• Datum vydání: 10. May 2010

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