Visual Analytics for Protein Folding / Nejlevnější knihy
Visual Analytics for Protein Folding

Kód: 06819047

Visual Analytics for Protein Folding

Autor Kush Kapila

In the field of bio-informatics, the analysis of§voluminous data is becoming increasingly crucial to§understanding the underlying biology and answering§important questions. Clustering techniques often in§combination with visualiza ... celý popis

1506


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Anotace knihy

In the field of bio-informatics, the analysis of§voluminous data is becoming increasingly crucial to§understanding the underlying biology and answering§important questions. Clustering techniques often in§combination with visualization techniques are§extensively used, say, to find the functions of§unknown genes through pattern detection and analysis.§ Similar to clustering of gene expression data is§that of clustering the characteristics of protein§folding dynamics. The mechanism of protein folding§remains largely a mystery. Currently, protein§folding dynamics is often characterized by§calculating the free energy landscape versus various§reaction coordinates such as the fraction of native§contacts, the radius of gyration and so on. We§present the development of a visual analytics tool,§PROTERAN, which enables one to view the changing§landscape of major protein fold states through the§metaphor of animated terrains. PROTERAN promotes the§use of an integrated approach towards understanding§the folding process via interactive visual analysis§of patterns of these reaction coordinates. In the field of bio-informatics, the analysis of§voluminous data is becoming increasingly crucial to§understanding the underlying biology and answering§important questions. Clustering techniques often in§combination with visualization techniques are§extensively used, say, to find the functions of§unknown genes through pattern detection and analysis.§Similar to clustering of gene expression data is§that of clustering the characteristics of protein§folding dynamics. The mechanism of protein folding§remains largely a mystery. Currently, protein§folding dynamics is often characterized by§calculating the free energy landscape versus various§reaction coordinates such as the fraction of native§contacts, the radius of gyration and so on. We§present the development of a visual analytics tool,§PROTERAN, which enables one to view the changing§landscape of major protein fold states through the§metaphor of animated terrains. PROTERAN promotes the§use of an integrated approach towards understanding§the folding process via interactive visual analysis§of patterns of these reaction coordinates.

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Biology, life sciences

1506

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