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Anotace knihy

This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.§§

Parametry knihy

Zařazení knihy Knihy v angličtině Medicine Pre-clinical medicine: basic sciences Medical genetics

• Plný název: Functional Nucleus
• Autor: David J. Bazett-Jones, Graham Dellaire
• Jazyk: Angličtina
• Vazba: Pevná
• Počet stran: 513
• EAN: 9783319388809
• ISBN: 3319388800
• ID: 02986365
• Nakladatelství: Springer International Publishing AG
• Hmotnost: 8985 g
• Rozměry: 235 × 155 × 32 mm
• Datum vydání: 25. October 2016

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