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Anotace knihy

There are currently only two structures of pores available, of -toxin from Staphylococcus aureus and hemolysin E from Escherichia coli. So what we know about these proteins was obtained over many years of intense experimentation. We have nevertheless, in the last couple of years, witnessed a significant rise in structural information on the soluble forms of pore-forming proteins. Surprisingly, many unexpected similarities with other proteins were noted, despite extremely low or insignificant sequence similarity. It appears that lipid membrane binding and formation of transmembrane channels is achieved in many cases by a limited repertoire of structures. This book describes how several of the important pore forming toxin families achieve membrane binding and which structural elements are used for formation of transmembrane pores. Our contributors have thus provided the means for a comparative analysis of several unrelated families.

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Biology, life sciences Biochemistry

• Plný název: Proteins
• Podnázev: Membrane Binding and Pore Formation
• Autor: Gregor Anderluh, Jeremy Lakey
• Jazyk: Angličtina
• Vazba: Pevná
• Počet stran: 172
• EAN: 9781441963260
• ISBN: 144196326X
• ID: 01423957
• Nakladatelství: Springer-Verlag New York Inc.
• Hmotnost: 482 g
• Rozměry: 259 × 173 × 18 mm
• Datum vydání: 21. May 2010

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