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Anotace knihy

Antimetabolites are key components in many significant therapeutics. They have pivotal effects in medicinal chemistry, and comprehensive applications in biochemistry and biotechnology. New Strategies Targeting Cancer Metabolism: Anticancer Drugs, Synthetic Analogues and Antitumor Agents presents up-to-date synthetic strategies for three categories of antimetabolites: antifolates, purines and pyrimidines, the main classes of antimetabolites which are integrated into various pharmaceutical agents. Many of these antimetabolites are considered potent chemotherapeutic agents which have great impact potential on the current medicinal research. These main classes of antimetabolites are use in the treatment of critical diseases including cancer, malignancies, chronic inflammatory diseases, malaria, psoriasis, gastrointestinal diseases, microbial, Alzheimer’s disease, influenza virus, hepatitis C (HCV), HIV, rheumatoid arthritis and other autoimmune diseases. New insights into a broad array of novel compounds are reviewed, well-recognized synthetic approaches are emphasized for further drug development and discovery, and the biological evaluation of novel synthesized compounds are included. This comprehensive reference is a valuable resource for medicinal chemists working in drug discovery and development, as well as pharmacologists and biochemists working in related fields. Only resource dedicated to synthetic strategies of antimetabolitesFeatures synthetic strategies for nucleosides and their analoguesIncludes coverage of purine-, pyrimidine-, and folate-based anticancer drugs

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Chemistry Organic chemistry

• Plný název: New Strategies Targeting Cancer Metabolism
• Podnázev: Anticancer Drugs, Synthetic Analogues and Antitumor Agents
• Autor: Galal Elgemeie, Reham Mohamed-Ezzat
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 628
• EAN: 9780128217832
• ID: 35761705
• Nakladatelství: Elsevier Science Publishing Co Inc
• Hmotnost: 1040 g
• Rozměry: 229 × 152 mm
• Datum vydání: 07. June 2022

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