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Více informací o knize Neurotrophic Factors and Their Receptors

• Parametry knihy
• Anotace
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Anotace knihy

Four GDNF ligands (GDNF, neurturin, artemin and persephin), and mesencephalic astrocyte-derived neurotrophic factor (MANF) and conserved dopamine neurotrophic factor (CDNF) protect midbrain dopaminergic neurons that degenerate in Parkinson's disease. Each GDNF ligand binds a specific coreceptor GDNF family receptor (GFR ), leading to the formation of a heterotetramer complex, which then interacts with receptor tyrosine kinase RET, the signalling receptor. The present work describes the structural and biochemical characterization of the GDNF-GFR 1 complex and the MANF and CDNF proteins.

Parametry knihy

• Plný název: Neurotrophic Factors and Their Receptors
• Podnázev: The structural and functional studies of GDNF and MANF/CDNF family of neurotrophic factors
• Autor: Vimal Parkash
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 92
• EAN: 9783838322469
• ID: 07045046
• Nakladatelství: LAP Lambert Academic Publishing
• Hmotnost: 155 g
• Rozměry: 220 × 150 × 6 mm
• Rok vydání: 2009

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