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Více informací o knize DNA Topoisomerases and Cancer

• Parametry knihy
• Anotace
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Anotace knihy

DNA topoisomerases represent an essential family of DNA processing enzymes and a large number of topoisomerase inhibitors are used clinically for the treatment of various human cancers. Novels drugs are in clinical development both against type I and type II topoisomerases. The book will include basic biochemical and structural reviews for the cancer-relevant topoisomerases. It will describe how topoisomerase dysfunctions can damage the genome and increase the risk of cancers, and the involvement of topoisomerases in programmed cell death. The book will also present the various topoisomerase inhibitors in clinical use and development and their molecular and cellular mechanisms of action.§

Parametry knihy

Zařazení knihy Knihy v angličtině Medicine Clinical & internal medicine Diseases & disorders

• Plný název: DNA Topoisomerases and Cancer
• Autor: Yves Pommier
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 443
• EAN: 9781461429630
• ISBN: 1461429633
• ID: 02544602
• Nakladatelství: Humana Press Inc.
• Hmotnost: 694 g
• Rozměry: 235 × 155 × 25 mm
• Datum vydání: 25. October 2013

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