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Více informací o knize Actin Polymerization in Apicomplexan

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• Anotace
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Anotace knihy

This book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements.The book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CP and CPbeta), cyclase-associated protein (CAP) and coronin 13-24 as potential drug targets against malaria.  As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design.Lastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics. 

Parametry knihy

Zařazení knihy Knihy v němčině Naturwissenschaften, Medizin, Informatik, Technik Medizin Klinische Fächer

• Plný název: Actin Polymerization in Apicomplexan
• Autor: Avinash Kale
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 116
• EAN: 9789811374524
• ISBN: 981137452X
• ID: 33446841
• Nakladatelství: Springer Nature Singapore
• Hmotnost: 214 g
• Rozměry: 235 × 155 × 7 mm
• Datum vydání: 26. November 2020

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