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Více informací o knize TGF- Signaling

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Anotace knihy

This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-beta from the basic principles to the practical applications. Chapters provide basic introduction of TGF-beta signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-beta signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Biology, life sciences Cellular biology (cytology)

• Plný název: TGF- Signaling
• Podnázev: Methods and Protocols
• Autor: Xin-Hua Feng, Xia Lin, Pinglong Xu
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 394
• EAN: 9781493949939
• ISBN: 1493949934
• ID: 18050003
• Nakladatelství: Humana Press Inc.
• Hmotnost: 7627 g
• Rozměry: 254 × 178 × 23 mm
• Datum vydání: 23. August 2016

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