Review: Synthetic methods and anti-microbial importance of thiazole / Nejlevnější knihy
Review: Synthetic methods and anti-microbial importance of thiazole

Kód: 02984803

Review: Synthetic methods and anti-microbial importance of thiazole

Autor Bapu Thorat, Vaishali Thorat, Vinay Joshi

Data on the synthesis of thiazoles systems from thioamide, thiourea, thiosemicarbazide, and labile sulfur was reviewed. The principal directions in the practical application of these substances are briefly discussed. Thiazole deri ... celý popis

1007


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Anotace knihy

Data on the synthesis of thiazoles systems from thioamide, thiourea, thiosemicarbazide, and labile sulfur was reviewed. The principal directions in the practical application of these substances are briefly discussed. Thiazole derivatives are important class of sulfur containing heterocyclic compounds, found in many potent biologically active molecules such as Cefdinir (antibacterial drug, semisynthetic third generation cephalosporin drug), flucloxacillin (androgenic steroid danazol), Pramipexole (The dopamine D2-agonist), Sulfathiazol (antimicrobial drug), Ritonavir (The HIV-1 protease inhibitor, antiretroviral drug), Famotidine (H2-receptor antagonist), Febuxostat (Xanthine oxidase inhibitor), Ziprasidone (Antipsychotic agent), etc. Thiazole derivatives were scanned against different bacteria and fungi, some of the derivatives shows strong anti-microbial activity was summarized.

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1007

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