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Anotace knihy

Protein Misfolding in Neurodegenerative Disease and Therapeutics Development is a comprehensive review of proteome homeostasis in neurons and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more. Discusses underlying cellular and molecular mechanisms altered in protein-associated neurodegenerative disordersDescribes methods for detection and analysis of protein aggregates.Features advancements in therapeutics and emerging techniques to treat these disordersCovers implications in a variety of neurodegenerative diseases including Alzheimer's, Parkinson’s, ALS, Creutzfeldt-Jakob disease, Cystic fibrosis, Gaucher's disease, Polyglutamine diseases including Huntington’s, and other related proteinopathies

Parametry knihy

Zařazení knihy Knihy v angličtině Medicine Other branches of medicine Pathology

• Plný název: Protein Misfolding in Neurodegenerative Diseases
• Autor: Neha Gogia, Sandeep Kumar Singh, Vidyadhara Devarunda Jaganath
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 300
• EAN: 9780443187162
• ISBN: 0443187169
• ID: 43723693
• Rozměry: 229 × 151 mm
• Datum vydání: 01. March 2024

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