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Více informací o knize Microbial Gene Essentiality: Protocols and Bioinformatics

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Anotace knihy

Microbial Gene Essentiality: Protocols and Bioinformatics contains a comprehensive collection of experimental and computational strategies and techniques for microbial genome-scale essentiality studies, developed and presented by the leading groups in the field. In addition to wet-lab protocols, the book describes (i) statistical methods essential for planning successful large-scale essentiality screens, as well for data evaluation and analysis; (ii) in-silico prediction of gene essentiality using genome-scale reconstructed metabolic models; and (iii) data integration and comparative analysis in the context of genomic databases. This volume provides researchers with a first-stop guide for choosing the most appropriate strategy for planned essentiality studies. Experimental and computational aspects are equally important in genome-scale gene essentiality analysis, as in all other genomic technologies, and Microbial Gene Essentiality: Protocols and Bioinformatics reflects both of these aspects. All protocols follow the successful Methods in Molecular Biology series format, each offering an introduction outlining the principles behind the techniques, step-by-step instructions, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding pitfalls, and are intended for both novice and expert scientists.

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Biology, life sciences Life sciences: general issues

• Plný název: Microbial Gene Essentiality: Protocols and Bioinformatics
• Autor: Svetlana Gerdes, Andrei L. Osterman
• Jazyk: Angličtina
• Vazba: Pevná
• Počet stran: 486
• EAN: 9781588293787
• ISBN: 1588293785
• ID: 01430385
• Nakladatelství: Humana Press Inc.
• Hmotnost: 1136 g
• Rozměry: 235 × 155 × 31 mm
• Datum vydání: 04. February 2008

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