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Anotace knihy

This volume details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, KRAS: Methods and Protocols aims to provide methods that will be instrumental in the development of future clinically approved KRAS therapeutics.

Parametry knihy

Zařazení knihy Knihy v angličtině Medicine Clinical & internal medicine Diseases & disorders

• Plný název: KRAS
• Podnázev: Methods and Protocols
• Autor: Andrew G. Stephen, Dominic Esposito
• Jazyk: Angličtina
• Vazba: Pevná
• Počet stran: 365
• EAN: 9781071638217
• ID: 44705107
• Nakladatelství: Springer, Berlin
• Hmotnost: 839 g
• Rozměry: 254 × 178 mm
• Datum vydání: 01. May 2024

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