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Anotace knihy

This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

Parametry knihy

• Plný název: High-Throughput Metabolomics
• Autor: Angelo D'Alessandro
• Jazyk: Angličtina
• Vazba: Pevná
• Počet stran: 459
• EAN: 9781493992355
• ISBN: 149399235X
• ID: 21161845
• Nakladatelství: Humana Press Inc.
• Hmotnost: 1106 g
• Rozměry: 32 × 183 × 31 mm
• Datum vydání: 23. May 2019

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