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Více informací o knize Genome Integrity

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• Anotace
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Anotace knihy

This is the first book to give a full overview on genome integrity in different species. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. Written by an international panel of experts, the book addresses the connection between genome integrity and human disease.Cells and viruses maintain a genome capable of multiplication, variation and heredity. A genome consists of chromosomes, each being built up of two complementary strands of nucleic acid known as DNA. Its chemical integrity, however, is under constant assault from metabolic mutagens, such as hydroxy-radicals, endonucleases, radiation, replication errors, and environmental mutagens. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. The volume begins with DNA replication and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed.

Parametry knihy

Zařazení knihy Knihy v angličtině Medicine Pre-clinical medicine: basic sciences Medical genetics

• Plný název: Genome Integrity
• Podnázev: Facets and Perspectives
• Autor: Dirk-Henner Lankenau
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 496
• EAN: 9783642072260
• ISBN: 3642072267
• ID: 01652390
• Nakladatelství: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
• Hmotnost: 752 g
• Rozměry: 159 × 233 × 30 mm
• Datum vydání: 24. November 2010

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