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Více informací o knize Characterisation of Jack Jumper Ant Venom - Definition of the Allergic Components and Pharmaceutical Development of Myrmecia pilosula (Jack Jumper) An

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Ant sting allergy in Australia is predominantly due §to the Myrmecia pilosula species complex (Jack §Jumper Ant, JJA) and venom immunotherapy has been §shown to be effective in preventing anaphylaxis to §the sting of this ant. This work describes the §development of a number of analytical §techniques to separate and characterise JJA venom §components. These techniques were then used to §determine the allergenicity of previously described §venom peptides in their native forms, identify §additional allergens and to update nomenclature used §to describe the allergens. They were subsequently §applied to the standardisation of venom prior to new §batches being used for the diagnosis and treatment §of JJA sting allergy. Myr p 2 was found to be the §only major allergen in JJA venom, whilst Myr p 1 and §Myr p 3 were minor allergens. There were an §additional five IgE-binding proteins that require §further characterisation before they can be named as §allergens. A standardisation procedure was validated §that is able to control the quality of venom so that §it complies with the requirements described in the §European Pharmacopoeia.

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Zařazení knihy Knihy v angličtině Medicine Other branches of medicine Pharmacology

• Plný název: Characterisation of Jack Jumper Ant Venom - Definition of the Allergic Components and Pharmaceutical Development of Myrmecia pilosula (Jack Jumper) An
• Autor: Michael Wiese
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 192
• EAN: 9783639051698
• ISBN: 3639051696
• ID: 06814663
• Nakladatelství: VDM Verlag Dr. Mueller E.K.
• Hmotnost: 263 g
• Rozměry: 229 × 152 × 10 mm
• Datum vydání: 29. August 2008

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