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Více informací o knize Adiponectin

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• Anotace
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Anotace knihy

Adiponectin is the name originated from its distinctive molecular characteristics ("adipo" + "nectin" = "adiponectin") as it is a product of novel gene apM1 which is specific to adipocytes and uniquely possess a collagen-like domain with a nectin-like adherent property. Adiponectin is the most abundant peptide secreted by adipocytes, whose altered levels play a central role in obesity-related diseases, including insulin resistance/type 2 diabetes and cardiovascular disease. It is known to exert anti-diabetic and anti-atherosclerotic effects via adiponectin receptors (Adipors); AdipoR1 and AdipoR2. Adiponectin has direct actions in liver, skeletal muscle and the vasculature. Adiponectin administration in humans and rodents has insulin-sensitizing, anti-atherogenic, and anti-in ammatory effects and in certain settings, also decreases body weight. Therefore, adiponectin replacement therapy in humans may suggest potential versatile therapeutic targets in the treatment of obesity, insulin resistance/type 2 diabetes, cardiovascular disease and atherosclerosis.

Parametry knihy

• Plný název: Adiponectin
• Podnázev: Implications in Health and Diseases
• Autor: V. N. Satyawali, Sanjeev Kumar Shukla
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 68
• EAN: 9786138920915
• ISBN: 6138920910
• ID: 25688601
• Nakladatelství: Scholars' Press
• Hmotnost: 113 g
• Rozměry: 229 × 152 × 4 mm
• Datum vydání: 20. January 2020

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