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Více informací o knize Target Validation in Drug Discovery

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• Anotace
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Anotace knihy

This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book.

Parametry knihy

Zařazení knihy Knihy v angličtině Technology, engineering, agriculture Industrial chemistry & manufacturing technologies Industrial chemistry

• Plný název: Target Validation in Drug Discovery
• Autor: Brian W. Metcalf, Susan Dillon
• Jazyk: Angličtina
• Vazba: Pevná
• Počet stran: 296
• EAN: 9780123693938
• ISBN: 0123693934
• ID: 04493729
• Nakladatelství: Academic Press
• Hmotnost: 820 g
• Rozměry: 260 × 184 × 24 mm
• Datum vydání: 01. September 2006

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