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Více informací o knize Incorporation of Heterocycles into Combinatorial Chemistry

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Anotace knihy

The author has summarized a decade of teaching combinatorial chemistry into this timely brief. The solid phase synthesis of unnatural heterocyclic alpha-amino acids is illustrated by practical examples starting from the ABCs of peptide synthesis explored in chapter one. Chapter two is concerned with the solid phase synthesis which is shown on various techniques - BillBoard, tea-bag, and Lantern devices, and demonstrated on heterocyclic examples and protocols. In the third chapter the tools for accelerating chemical synthesis - solid phase and liquid phase - are reviewed. Here the techniques of parallel refluxing (including microwave and flow technique) and parallel separation (filtration, centrifugation, evaporation, and chromatography) are described. In the chapters 4 and 5 the author goes on to describe how the liquid phase synthesis of heterocycles (reductive amination and Ugi reaction of heterocycles) is illustrated with the use of semi-automated protocols. Finally, the design of combinatorial libraries of heterocycles is reviewed including the original author's findings.

Parametry knihy

Zařazení knihy Knihy v angličtině Technology, engineering, agriculture Industrial chemistry & manufacturing technologies Industrial chemistry

• Plný název: Incorporation of Heterocycles into Combinatorial Chemistry
• Autor: Eugene V. Babaev
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 117
• EAN: 9783319500133
• ISBN: 3319500139
• ID: 15195089
• Nakladatelství: Springer International Publishing AG
• Hmotnost: 2117 g
• Rozměry: 235 × 155 × 8 mm
• Datum vydání: 15. December 2016

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