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Více informací o knize Total Synthesis of Callipeltin E and Towards Papuamide B

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• Anotace
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Anotace knihy

Callipeltins and Papuamides -novel families of cyclic§depsipeptides- were shown to possess potent anti-HIV§activity as well as cytotoxicity against several §multidrug resistant cancer cell lines. The novel §structural features and diverse biological effects §of these peptides metabolites have generated §considerable interest among synthetic chemistry §groups. In this book, discovery of the lanthanide §catalyzed transamidation of Fmoc protected lactams, §solid-phase synthesis and configurational §reassignment of Callipeltin E, synthesis of N-Fmoc-§(2S,3S,4R)-3,4-dimethylglutamine and an efficient §method for the on-resin synthesis and §macrocylization of a simplified Papuamide B model §system are summarized.

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Chemistry

• Plný název: Total Synthesis of Callipeltin E and Towards Papuamide B
• Autor: Selcuk Calimsiz
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 128
• EAN: 9783639103298
• ISBN: 3639103297
• ID: 06819315
• Nakladatelství: VDM Verlag
• Hmotnost: 181 g
• Rozměry: 229 × 152 × 7 mm
• Datum vydání: 06. November 2008

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