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Více informací o knize Nanoparticle Induced Inflammatory Signaling in the Lung

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Anotace knihy

The cardiorespiratory system is designed to facilitate the exchange of gases, such as oxygen and carbon dioxide, maintain acid-base and electrolyte balance, and serve as an important mechanism for filtering potentially harmful environmental materials. Respiratory exposure to nanoparticles, in an environmental or industrial setting, can induce the expression of inflammatory mediators in various cell types of the lung. The research detailed in this book provides a possible mechanism by which particle-induced signaling in alveolar Type II epithelial cells may occur and suggests that the epithelial cell signaling mechanism initiates and propagates a pro-inflammatory pathway that can lead to pulmonary fibrosis. Pulmonary inflammation, resulting from particulate exposure, is an interesting model in which to study inflammation, dysregulated tissue repair and carcinogenesis. With the advent of nanoparticle technology, in industrial and consumer products, toxicological assessment of Aerosil200 particles may become a standard against which to measure the effects of other nanoparticles.

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Biology, life sciences Biochemistry

• Plný název: Nanoparticle Induced Inflammatory Signaling in the Lung
• Podnázev: Mechanism of Aerosil200 Particulate Induced Inflammatory Gene Expression in Alveolar Epithelial Cells
• Autor: Madhuri Singal
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 232
• EAN: 9783639215526
• ISBN: 3639215524
• ID: 06829437
• Nakladatelství: VDM Verlag
• Hmotnost: 345 g
• Rozměry: 229 × 152 × 13 mm
• Datum vydání: 13. July 2010

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