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Anotace knihy

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector.§§The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).§§The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.§§Concisely summarizes the therapeutic implications of recent, large-scale epigenome studies, including the cancer epigenome atlas§Discusses targeted isoform specific versus pan-specific inhibitors, a rational drug design approach to epigenetics relevant to pharmacoepigenetic clinical applications§Covers new findings in the interplay between cancer stem cells (CSCs) and drug resistance, demonstrating that epigenetic machinery is a candidate target for the eradication of these CSCs

Parametry knihy

Zařazení knihy Knihy v angličtině Medicine Pre-clinical medicine: basic sciences Anatomy

• Plný název: Epigenetic Cancer Therapy
• Autor: Steven Gray
• Jazyk: Angličtina
• Vazba: Pevná
• Počet stran: 748
• EAN: 9780128002063
• ISBN: 0128002069
• ID: 09240325
• Nakladatelství: Elsevier Books
• Hmotnost: 1722 g
• Rozměry: 200 × 242 × 42 mm
• Datum vydání: 24. August 2015

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