Mohlo by se vám také líbit

Více informací o knize Discovery of HIV-1 Integrase Inhibitors

• Parametry knihy
• Anotace
• Oblíbené z jiného soudku

Nákupem získáte 148 bodů

Anotace knihy

Highly active antiretroviral therapy (HAART) is the current treatment regimen for HIV/AIDS, a disease that has claimed millions worldwide. HAART is a cocktail that inhibits different stages of the viral life cycle targeting protease, reverse transcriptase, and often includes anti-fusion inhibitor enfurvitide. The addition of HIV-1 integrase (IN) inhibitor raltegravir to HAART reveals a decrease of the virus to near undetectable levels in treatment-experienced patients. Although these successes are encouraging for antiviral therapy, specific mutations resistant to raltegravir have also appeared. Drug resistant mutations is the inevitable signature of HIV with a merry-go-round history of antiviral drug development and viral evolution, highlighting the need to identify new leads for IN inhibition. Absent of a cellular

Parametry knihy

Zařazení knihy Knihy v angličtině Medicine Other branches of medicine Pharmacology

• Plný název: Discovery of HIV-1 Integrase Inhibitors
• Podnázev: Furan and Sulfonamide-based Integrase Inhibitors
• Autor: Tino Sanchez
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 60
• EAN: 9783639302813
• ISBN: 3639302818
• ID: 06837270
• Nakladatelství: VDM Verlag
• Hmotnost: 100 g
• Rozměry: 229 × 152 × 4 mm
• Datum vydání: 18. November 2010

Oblíbené z jiného soudku

---

---

---