Kód: 13301406
It is well known that heterocyclic derivatives represent almost half of the several million chemical species discovered to date. The importance of these compounds in many branches of chemistry ensures further investigation ... celý popis
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It is well known that heterocyclic derivatives represent almost half of the several million chemical species discovered to date. The importance of these compounds in many branches of chemistry ensures further investigation and attention. This series aims to stimulate creativity and innovation by including research by leading authorities. As well as highlights of interesting developments in specific areas, there are also comprehensive reviews reporting the overall state-of-the-art. Targets in Heterocyclic Systems Volume 6 will be welcomed by researchers and industrialists with an interest in the synthesis, reactivity and medicinal properties of heterorings. TOC: Enantioselective ring expansion via aziridinium intermediates. Synthesis of substituted piperidines from substituted pyrrolidines. Synthetic applications; The formation of the carbon-carbon bond catalysed by metalloporphyrins; Pyrazoles as drugs: facts and fantasies; Recent advances in the synthesis of saturated nitrogen heterocycles using N-acyliminium ion intermediates; Reductive opening of heterocycles with lithium metal as a source of functionalised organolithium compounds: synthetic applications; Furan-2,3-diones: convenient synthons in heterocyclic chemistry; Metal-catalysed cyclocarbonylation reactions for the synthesis of lactones and lactams; Preparation and synthetic applications of (S)- and (R)-N-BOC-N,O-isopropylidene-α-methylserinals; Synthesis and reactivity of 1-(2,4,6-trialkylphenyl)phospholes with a flattened P-pyramid; Chiral β-aminoalcohols and derivatives in the asymmetric synthesis of the tetrahydroisoquinolines: Stereoselective synthesis of nitrogen heterocycles of enantiopure 3-hydroxy esters through electrophilic amination; Recent trends in synthesis of heterocycles using ketene-dithioacetals with electron attracting groups; Recent developments in the chemistry of 4,5-dihalo-3(2H)-pyridazinones; Synthesis of heterocycles from allenes by intramolecular ring closure.
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